Made in Korea.
From the epicenter of beauty and skincare innovation, delivering on the Korean beauty philosophy of natural-looking results.
Now FDA Approved
K-TOX
Korea’s #1 best-selling
Korea’s #1 best-selling
neurotoxin is here.1
Born from the world's most advanced aesthetics culture and grounded in science.
1 Data on file, Hugel, Inc. Based on total reported revenue 2016–2025.
Letybo® is a neurotoxin made in Korea, used by millions worldwide and now available in the United States. With a few injections from a qualified specialist, Letybo® works beneath the surface to temporarily improve the appearance of moderate to severe frown lines, helping the area between the brows look visibly smoother.
44+ Million Treatments2
70+ Countries3
The Standard in K-Beauty
2 Data on file. Total toxin sales 2010–2026. Hugel; May 2026. 3 Data on file. List of approved countries. Hugel Inc. 2026.
K-Beauty's Top Neurotoxin
Just Launched in the U.S.
— As Seen In NewBeauty
Proven results, backed by data and clinical experience
Actual Letybo® patient in her 30s.
After (Day 3)
Actual Letybo® patient in her 30s.
After (Day 3)
Actual Letybo® patient in his 40s.
After (4 weeks)
Actual Letybo® patient in her 50s.
After (4 months)
Actual patients at maximum frown. Unretouched photos. Individual results may vary.
Visible results in as little as 1–3 days*
*In a Phase 3 clinical study, 24% of patients reported seeing improvement within the first 24 hours, with 75% of patients reporting improvement by Day 3.4
Lasting up to 4 months**
**In a Phase 3 clinical study, time to retreatment for Letybo® patients was an average of 127 days4
FDA
Approved
Approved
Used by millions of patients and providers worldwide before reaching U.S. clinics.
Across 3 clinical studies in 1,200+ patients, the majority of patients treated with Letybo® observed a ≥2 grade improvement by physician and patient assessments at week 4.5
4 Mueller DS, Prinz V, Adelglass J, Cox SE, Gold MH, et al. Efficacy and safety of letibotulinumtoxinA in the treatment of glabellar lines: a randomized multicenter, placebo-controlled Phase 3 study. ASJ. 2022:42(6):677-688. Doi: 10.1093/asj/sjac019.
01
02
Proven Results
Born from Korea's advanced aesthetics culture, Letybo® has been approved in over 70 countries and has 15+ years of global clinical experience.
03
A provider who knows you.
Inspired by the Korean approach to beauty, Letybo® is offered by providers committed to customized treatment plans that enhance, rather than change, what makes each patient unique.
Ready
to see what
Letybo®
can do?
The first step is a conversation with a qualified provider who can help you decide if Letybo® is right for you.
K-TOX
Ask your provider about Korea's #1 Best-Selling Neurotoxin1 Today.
1 Data on file, Hugel, Inc. Based on total reported revenue 2016–2025.
Let's connect.
Have questions about Letybo®? We're here to help.
Fill out the form and a member of the Letybo® team will be in touch.
INDICATION
LETYBO® is a prescription medicine for adults that is injected into muscles to temporarily improve the look of moderate to severe frown lines between the eyebrows (glabellar lines).
IMPORTANT SAFETY INFORMATION
LETYBO® may cause serious side effects that can be life threatening. Call your healthcare provider or get medical help right away if you have any of these problems after treatment with LETYBO®:
Problems swallowing, speaking, or breathing, due to weakening of associated muscles can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months.
Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms that include loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.
Do not receive LETYBO® if you are allergic to any of the ingredients in LETYBO® (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as MYOBLOC® (rimabotulinumtoxinB), BOTOX®/BOTOX® COSMETIC (onabotulinumtoxinA), DYSPORT® (abobotulinumtoxinA), XEOMIN® (incobotulinumtoxinA), JEUVEAU® (prabotulinumtoxinA-xvfs), or DAXXIFY® (daxibotulinumtoxinA-lanm); or have a skin infection at the planned injection site.
LETYBO® dosing units are not the same as, or comparable to, any other botulinum toxin product.
Tell your healthcare provider about all your medical conditions, including side effects from botulinum toxin products, including dry eye; breathing, swallowing, bleeding, or heart problems; plans to have surgery; weakness of forehead muscles, drooping eyelids; have had surgery on your face; are pregnant or breastfeeding or plan to become pregnant or breastfeed.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using LETYBO® with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your healthcare provider that you have received LETYBO® in the past.
Especially tell your healthcare provider if you have received any other botulinum toxin product in the last 4 months or any in the past, and exactly which product you received (such as MYOBLOC®, BOTOX®/BOTOX® COSMETIC, DYSPORT®, XEOMIN®, JEUVEAU®, or DAXXIFY®). LETYBO® may cause serious side effects, including allergic reactions (such as itching, rash, hives, wheezing, trouble breathing, or dizziness or feeling faint), heart problems (such as irregular heartbeat and heart attack), and eye problems (including dry eye, reduced blinking, and corneal problems). Tell your healthcare provider or get help right away if you experience a serious side effect. No serious side events of distant spread of toxin effect associated with dermatologic use of LETYBO® have been reported in clinical studies at the dose of 20 Units for glabellar lines. The most common side effect of LETYBO® was headache.
These are not all the possible side effects of LETYBO®. For more information, see the full Prescribing Information including Boxed Warning, and refer to the Medication Guide or talk with your doctor. To report side effects associated with LETYBO®, please call 1-877-390-2906. You may also report side effects to the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.
US-LETI-2600010 06/2026
Certain images in this material were created using artificial intelligence for illustrative purposes only. Before and After imagery is unretouched and represents actual patients.